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Chronic Lymphocytic Leukemia News

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Whether on watch-and-wait or treatment regimens, patients with chronic lymphocytic leukemia had significantly impaired quality of life compared with age-matched healthy control subjects, according to a study published online in the European Journal of Haematology. Researchers from the Postgraduate…
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Among younger patients with chronic lymphocytic leukemia (CLL) receiving one of the four most common treatment regimens, 59% experienced at least one incident adverse event, according to a study in Advances in Therapy.  The retrospective cohort study included 1706 adults with commercial insurance…
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In patients with relapsed/refractory chronic lymphocytic leukemia, early venetoclax discontinuation was associated with suboptimal outcomes but venetoclax interruption was not, according to a poster from the 2020 ASCO Virtual Scientific Program.   “Venetoclax + rituximab has a manageable safety…
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Prognosis indexes (PIs) may be helpful at improving clinical staging and assisting physicians in their practice, but more research with larger cohorts of patients are needed to fully understand the benefits of using PI to assess the time to first treatment in patients with early-stage (Binet A)…
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In a recent study, researchers examined the outcomes of patients with chronic lymphocytic leukemia (CLL) treated with CD19-specific Chimeric antigen receptor T-cell (CAR-T) therapy—specifically focusing on overall survival and progression following CART-T treatment. "This data sets a benchmark for…
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Researchers recently studied the influence genetics have on chronic lymphocytic leukemia (CLL) patients’ response to anti-CD19 chimeric antigen receptor (CAR)-T cell therapy. Veronika Mancikova, PhD, Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic, and…
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Single-agent ibrutinib was found to have both sustained responses and long-term tolerability for the treatment of first-line or relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), according to a study published in Clinical Cancer Research. John C Byrd, MD,…
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According to study findings, managing hematologic cancers—including chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and multiple myeloma—similar to chronic conditions, has proven to be successful. Researchers of a recent study published in the Journal of Managed Care &…
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Just 29% of adults underwent treatment for chronic lymphocytic leukemia (CLL) in the year and a half following diagnosis, according to a study published in Cancer Medicine.  “The finding that nearly two‐thirds of patients did not receive a cancer‐directed therapy after CLL diagnosis suggests that…
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Delaying cancer progression was associated with substantially reduced health care costs in patients with chronic lymphocytic leukemia, acute myeloid leukemia, and non‐Hodgkin's lymphoma, according to a study published in The Oncologist.  “New treatments that delay disease progression in patients…
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